November 19-22, 2003

Ljubljana, Slovenia

Electroporation based Technologies and Treatments


Key lectures and content of the course:

Cells and tissues in electric fields

D. Miklavèiè

  • Biological cell and its plasma membrane
  • Resting and induced transmembrane voltage
  • Static and dynamic electric fields in biological tissues
  • Electroporation, part 1

    E. Neumann

  • The history of electroporation
  • Elementary theory of electroporation
  • Electroporation of lipid bilayers
  • Electroporation of vesicles
  • Electroporation, part 2

    J. Teissié

  • Electroporation of cells in suspension
  • Electroporation of cells in 2D tissue model
  • Parameters that determine the efficiency of electroporation in vitro
  • Electroporation, part 3

    L.M. Mir

  • Electroporation of cells in tissue
  • Methods for detecting cell electropermeabilization in vivo
  • Development of devices and electrodes

    D. Miklavèiè

  • Devices for in vitro and in vivo experimental work
  • Devices for clinical purposes
  • Electrodes for in vitro and in vivo
  • Application of electroporation in electrochemotherapy of tumors

    G. Ser¹a

  • Experiments in vitro
  • Experiments in vivo
  • Current clinical applications
  • Future perspectives
  • Application of electroporation in gene transfection

    L.M. Mir,

  • Gene transfection in vitro
  • J. Teissié

  • Gene transfection in vivo
  • Future perspectives
  • Application of electroporation in biotechnology

    J. Teissié

  • Water sterilization
  • Other applications
  • Future perspectives
  • Electroporation in transdermal drug delivery

    V. Preat

  • Transdermal drug delivery using electroporation
  • Intradermal and topical delivery of DNA by means of electroporation
  • Short presentations of selected abstracts

    Round table on electroporation based technologies and treatments